ICSI-IVF is the latest ART procedure where a single good quality sperm is picked up with a fine glass needle and is injected directly into each egg under micro-manipulator Very few sperm are required and the ability of the sperm to penetrate the egg is no longer important as this has been assisted by the ICSI technique.
In traditional IVF, the eggs and sperm are combined in a dish and the sperm prepares the egg 'naturally'. However to have a possibility that this will happen, extensive quantities of effectively swimming ordinary sperm are required. For some couples, the quantity of appropriate sperm accessible might be exceptionally constrained or there might be different variables forestalling treatment, so regular IVF is impossible. ICSI has given a would like to these couples.
ICSI alludes to the lab technique where a solitary sperm is gotten with a fine glass needle and is infused specifically into each egg. This is completed in the research facility by experienced embryologists utilizing pro hardware. Not very many sperm are required and the capacity of the sperm to enter the egg is not any more imperative as this has been helped by the ICSI procedure. ICSI does not ensure that treatment will happen as the ordinary cell occasions of preparation still need to happen once the sperm has been put in the egg.
From a patient point of view, experiencing an ICSI treatment cycle is precisely the same as a traditional IVF cycle. Patients ought to however know about the dangers related with ICSI.
- Stimulation of the ovaries to support advancement and development of the eggs.
- Retrieval of the eggs.
- Fertilisation of the eggs and culture of the developing lives.
- Transfer of the developing lives once again into the uterus.
- These steps are depicted all the more completely under IVF.
The first step in the process after undergoing through Investigations where the ovaries of female partner are stimulated by injection and medication for 10-12 day This continues until the eggs are mature. The stimulation process is controlled through ultrasound scan and E2 level. Then HCG administered .during this process couple will have to visit the hospital on daily basis.
After administering HCG you will be given time and date for egg retrieval. Based on the doctor’s assessment, a date is fixed for egg collection and the female partner’s eggs are removed under vaginal ultrasound guided probe and the follicles are aspirated. There are no cuts on the abdomen.
Once the eggs are collected then embryologist starts working on healthy oocytes and each oocyte is injected with selected sperm of the partner. The dishes are left in the incubator overnight to allow fertilization to take place. Usually about 60%-70% of the eggs collected will be fertilized. After 2-3 days, the embryos will usually consist of four to eight cells, and at this stage are ready for transfer to the uterus. Under the ultrasound guidance, three good quality embryos are carefully selected and carefully transferred through the vagina and cervix to the uterus, where implantation begins.
After 15 days of transfer the female partner is asked to undergo beta HCG test to confirm the Pregnancy. If the pregnancy is confirmed then they are called after 15 days for fetal heart scan.